BBC   by Andrew Harding                                    Dec. 2, 2014

FREETOWN, Sierra Leone --

... "By now, everyone knows about Ebola; and nobody with symptoms should, logically, be dying at home or on the street anymore.

Sometimes suspected Ebola cases are not reported to the health authorities

They should all have been taken to hospital.

But to understand why that is not happening, all you have to do is drive to any of the impoverished suburbs of Freetown..."

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http://www.bbc.com/news/world-africa-30279932

With trials under way, scientists are working out how to give vaccines in affected regions

NATURE   By Ewan Callaway                                                                                                 Dec. 2, 2014

Safety trials of Ebola vaccines are starting to return results: at least one is known to be safe and to summon an immune response against the virus.

The challenge now is to use the results to guide the larger studies that will reveal whether the vaccines work.

“The immune responses are there,” says infectious-disease researcher Adrian Hill, director of the Jenner Institute in Oxford, UK. “The tough call is whether they’re enough to protect humans against Ebola.”

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http://www.nature.com/news/positive-results-spur-race-for-ebola-vaccine-1.16468

DISCOVER MAGAZINE    By Kari Lydersen                                                                              Dec. 2, 2014
.....redicting the trajectory of Ebola rather than playing catching-up could do much to help prevent and contain the disease. Some experts have called for prioritizing mobile treatment units that can be quickly relocated to the spots most needed. Figuring out where Ebola is likely to strike next or finding emerging hot spots early on would be key to the placement of these treatment centers.

But such modeling requires data, and lots of it.  And for stressed healthcare workers on the ground and government and non-profit agencies scrambling to combat a raging epidemic, collecting and disseminating data is often not a high priority.

ASSOCIATED PRESS                                                                                                        Dec. 2, 2014 

BETHESDA, Maryland  — Declaring the "fight is nowhere close to being over," President Barack Obama on Tuesday heralded strides in the effort to confront Ebola in West Africa and in protecting the U.S. against the spread of the deadly virus. He said squelching the disease remains an urgent priority even if the American public's attention has shifted elsewhere.

"We cannot let down our guard, even for minute," Obama said. "We can't just fight this epidemic, we have to extinguish it."

Obama spoke after touring the National Institutes of Health in Washington's Maryland suburbs where he witnessed advances in Ebola-fighting research. He highlighted the NIH's progress in developing an Ebola vaccine, calling the initial results "exciting" while cautioning that there are "no guarantees" about the vaccine's ultimate success.

NIH researchers last week reported that the first safety study of a vaccine candidate found no serious side effects, and that it triggered signs of immune protection in 20 volunteers. U.S. health officials are planning much larger studies in West Africa to try to determine if the shots really work...

IRIN                                                              Dec. 1, 2014

DAKAR--It is next to impossible to avoid physical contact in an overcrowded prison. In Sierra Leone, heavily congested jails and a worsening Ebola outbreak make a potentially lethal combination. So how do you keep inmates safe?

                          Decongesting prisons in Sierra Leone to lower Ebola threat.Photo: Hannah McNeish/IRIN

Some of the safeguards against the virus are: A 21-day quarantine for fresh detainees before joining the old timers; training prison health workers and inmate leaders on Ebola prevention; and providing health and safety education and equipment.

Such measures, and others, have so far helped keep the virus out of Sierra Leone’s 17 prisons and three juvenile offenders’ homes, said Mambu Feika, head of NGO Prison Watch Sierra Leone (PWSL), which is spearheading a three-month programme to prevent Ebola transmission in prisons.

See full story

World Bank Meanwhile lowers growth forecasts.

(See link below to World Bank Report)

ASSOCIATED PRESS                                                                                               Dec. 2, 2014
By JONATHAN PAYE-LAYLEH and SARAH DiLORENZO

MONROVIA, Liberia (AP) — The international response to Ebola is still too slow and piecemeal, Doctors Without Borders warned Tuesday, as officials said the disease is crippling the economies of the three West African countries hardest hit....

"Foreign governments have focused primarily on financing or building Ebola case management structures, leaving staffing them up to national authorities, local health care staff and NGOs (non-government organizations) which do not have the expertise required to do so," said the group, which is a primary provider of treatment in the outbreak, said in a statement Tuesday.

It reiterated its call for countries with biological-disaster response teams to deploy them.

NEW YORK TIMES  By Sheri Fink and  Somini Sengupta                                                       Dec. 2, 1014

GENEVA — The World Health Organization expressed doubt on Monday about achieving important United Nations benchmarks in battling Ebola, saying the year-end goals of isolating and treating all patients and safely burying all the dead would be major challenges.

REUTERS  -- By Roberta Rampton                                                                      Dec. 2, 2014

WASHINGTON --President Barack Obama on Tuesday will press Congress to approve $6.18 billion in emergency funding to help fight the Ebola outbreak in West Africa and prepare U.S. hospitals to handle future cases.

Most of the request is aimed at the immediate response to the disease at home and abroad. But the package also includes $1.5 billion in contingency funds - money that could become a target if lawmakers decide to trim the bill.

"That is the part of the package that is most at risk," said Sam Worthington, president of InterAction, an alliance of U.S. non-governmental aid groups.

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WHO targets on isolating patients and medical burials missed as NGO warns virus has reduced country to ‘a nation of mere beggars’

THE GUARDIAN   By  Lisa O'Carroll                                                                                           Dec. 1, 2014

FREETOWN --SIERRA Leone-- 
Ebola continues to surge in Sierra Leone, with the number of cases quintupling in Freetown alone in the past two months, according to new figures.

A health worker gives a drink to a young patient at the Kenema treatment centre, Sierra Leone. Photograph: Francisco Leong/AFP/Getty Images

BBC    By   Mark Doyle                                                                                                        Dec. 1, 2014

Tony Banbury declined to say if targets he had set in the fight against Ebola, to be achieved by Monday, had been met.

The targets were for the proportion of people being treated and for the safe burial of highly infectious bodies.

In October, Mr Banbury told the UN Security Council that by 1 December, "70% of all those infected by the disease must be under treatment and 70% of the victims safely buried if the outbreak is to be successfully arrested".

Mr Banbury said the 70% targets were being met in "the vast majority" of areas in the three worst-affected countries - Guinea, Sierra Leone and Liberia.

"But in some areas", he said, "including here in Sierra Leone - especially in the capital Freetown and in the town of Port Loko - we are falling short. And it is in those areas where we really need to focus our assets and our capabilities".

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nejm.org

A collection of articles and other resources on the Ebola outbreak, including clinical reports, management guidelines, and commentary.

CLICK HERE - NEJM Ebola Outbreak page, where all content is FREE

https://www.facebook.com/TheNewEnglandJournalofMedicine/posts/10152498380218462

DESIGN & TREND  by Randall Mayes                                                                             Nov. 29, 2014

Over the last decade, we have witnessed the emergence of Superbugs, various strains of bird flu and now Ebola, which do not have geographical borders.

Consequently, there is a pressing need for international cooperation to control these pandemics.

In a new study, researchers have identified obstacles that are currently preventing the world from sharing health data, reports Science Daily.

While performing a literature search for the study, an international group of researchers discovered over 1,400 scientific articles related to sharing public health data. From those articles, they found two broad categories that need to be addressed.

Read comlete story
http://www.designntrend.com/articles/28008/20141129/urgent-need-improved-infrastructure-share-health-data.htm

Link to article  in Science Daily
http://www.sciencedaily.com/releases/2014/11/141125102102.htm

wellcome.ac.uk - November 28, 2014

A rapid, point-of-care diagnostic test for the Ebola virus will be trialled in the coming weeks at the Ebola treatment centre in Conakry, Guinea. The trial is one of six health research projects that have been jointly funded by the Wellcome Trust and the UK government.

The 15-minute Ebola test is six times faster than similar tests currently in use and aims to speed up the diagnosis of Ebola cases. Early detection of Ebola leads to better infection control as medical staff can identify and isolate confirmed cases of Ebola faster, and start treating patients sooner. Ultimately, a faster test could reduce Ebola transmission and mortality.

The project is supported through a joint Department for International Development (DFID) and Wellcome Trust fund for rapid health research during the Ebola outbreak. The six projects are managed by Enhancing Learning & Research for Humanitarian Assistance (ELRHA).

REUTERS                                                                                                                      NOV. 28, 2014

LONDON --Men who recover from Ebola should abstain from sex for three months to minimize the risk of passing the virus on in their semen, the World Health Organization (WHO) said on Friday.

Ebola, a disease that has infected and killing thousands in a vast epidemic in West Africa, normally spreads via bodily fluids such as blood, saliva and faeces. Although sexual transmission of Ebola virus disease has never been documented, the virus has been detected in the survivors' semen.

"Men who have recovered from Ebola virus disease should be aware that seminal fluid may be infectious for as long as three months after onset of symptoms," the WHO said in a statement....

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http://www.reuters.com/article/2014/11/28/us-health-ebola-sex-idUSKCN0JC0UP20141128

NEW YORK TIMES   By Jeffrey Gettleman                        Nov.28, 2014

KISSI TOWN, Sierra Leone-- ...While health officials say they are making headway against the Ebola epidemic in neighboring Liberia, the disease is still raging in Sierra Leone, despite the big international push. In November alone, the World Health Organization has reported more than 1,800 new cases in this country, about three times as many as in Liberia, which until recently had been the center of the outbreak....

On Freetown’s outskirts, burly youth are setting up roadblocks. The police are nowhere to be found. The young men barricade the road brandishing digital thermometers. Credit Daniel Berehulak for The New York Times