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Ebola Innovation for Impact - 2015 Data Strengthening, Situational Awareness & Coordination Working Group Sessions

                                                                

1:00-5:00 pm, July 8, 2015

Manhattan Room, One UN Plaza, Second Floor

44th St. and 1st Ave., New York City

Agenda

On Wednesday July 8, 2015, an afternoon session will address Ebola response & recovery data strengthening, situational awareness, and coordination.  This working session will be held at U.N. headquarters in New York or a facility nearby from 1:00 PM to 5:00 PM.

Following are the proposed elements of the July 8 afternoon session:

1:00 PM           40 mins                        Opening Plenary Session

            An Overview of West Africa’s Current & Emerging Infrastructures

                        Barbara Bentein           UNICEF

                        Juliet Benford               Anthrologica

                        Sara Glass                   USAID, Global Development Lab

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Ebola Survivors May Be the Key to Treatment - For Almost Any Disease

submitted by George Hurlburt

      

A group of volunteer medical workers carry the bodies of Ebola victims to a car in order to bury them in Kptema graveyard in Kenema, Sierra Leone, on August 24, 2014. Mohammed Elshamy/Anadolu Agency/Getty Images

wired.com - by Erica Check Hayden - June 30, 2015

. . . The patients held the answer. If they survived, they carried antibodies that targeted the very viruses that had almost killed them. The samples he’d been working with didn’t contain antibodies, but if he could get blood from survivors, he might be able to figure out how to make the same antibodies that their immune systems had produced. It would not be easy or fast, but he couldn’t stand by while more people lost their lives—if not in this outbreak, then in the next one, or the next one after that. It was time for a new plan. . . .

. . . Once your body knows how to make antibodies specific to a disease, it never forgets . . . So physicians use survivor serum in the hope that amid the trillions of antibodies an adult human can make, the ones that fight a specific disease will be in the mix. It’s not a new idea.

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Video - The Story of Ebola

CLICK HERE - Global Health Media - The Story of Ebola - English

June 26, 2015

This animation—produced in collaboration with International Federation of Red Cross and Red Crescent Societies, UNICEF, and Yoni Goodman—brings to life key messages that help people see and understand how Ebola spreads and how to protect themselves and their communities.

CLICK HERE - About the film:

The story features a young girl whose grandfather dies from Ebola and puts the rest of her family at risk. The film makes visible the invisible Ebola germs to help people see and understand how Ebola spreads and how to protect themselves. Critical messages are woven through the story so that people better understand Ebola, see themselves within the context of an outbreak, and see how to act in ways that can keep themselves safe from the disease and protect their communities.

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Finger-prick, blood test for Ebola takes just minutes

THE WASHINGTON POST by

Public health officials may soon be able to screen patients for Ebola at border crossings and hospitals with a finger-prick blood test that takes mere minutes.

The development of the rapid diagnostic test, reported in The Lancet Thursday, represents a significant victory for scientists around the world who have been experimenting over the past year with all manner of vaccines, treatments and other ways of eradicating the virus.

Developing a way of confirming Ebola in a patient has been one of the top priorities. In the early stages the symptoms -- chest pain, cough, nausea -- can look like many other illnesses, making it very difficult for doctors to triage -- to determine who should be quarantined and who to send home. It can often take days or longer for laboratory tests, the current standard, to return a positive or negative result.

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Blood, Sweat and Tears: Study Will Watch Ebola Survivors

NBC NEWS   by Maggie Fox                              June 17, 2015         

Does Ebola stay in your eyes after you recover? Can it spread via semen? Why does it cause achey joints?

U.S. researchers are launching a study in Liberia to take a look at survivors of the deadly virus to see just how common these long-term effects are, and whether they contribute to outbreaks.

"To unravel the many unknowns, we have expanded the focus of our partnership with Liberia's Ministry of Health to include research on the long-term health effects of Ebola virus disease, in addition to our ongoing efforts to find an effective preventive vaccine and treatments for Ebola virus disease," said Dr. Tony Fauci, director of the National Institute of Allergy and Infectious Disease.

Liberia's health ministry and the NIAID will be studying 1,500 Ebola survivors and 6,000 of their close contacts. They'll look at sweat, tears, semen and other bodily fluids in the survivors and follow everyone for as long as five years.

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Readability of Ebola Information on Websites of Public Health Agencies, United States, United Kingdom, Canada, Australia, and Europe

CDC IED JOURNAL  by    Enrique Castro-Sánchez , Elpiniki Spanoudakis, and Alison H. Holmes    Volume 21, Number 7- July 2015                                          

 Public involvement in efforts to control the current Ebola virus disease epidemic requires understandable information. We reviewed the readability of Ebola information from public health agencies in non–Ebola-affected areas. A substantial proportion of citizens would have difficulty understanding existing information, which would potentially hinder effective health-seeking behaviors....

Several factors, including readability of information provided (8), can help reduce health literacy deficits...It is recommended that health information materials should be written at a level typically understandable by an 11-year-old person ... anxiety or panic attributed to a highly virulent infection, such as Ebola, might hinder comprehension of related information (11).

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Favipiravir—a prophylactic treatment for Ebola contacts?

THE LANCET byMichel Van Herp, Hilde Declerck and Tom Decroo June 13, 2015

.. the efficacy of candidate Ebola vaccines for primary prevention has not been proven.2 Furthermore, in communities in which Ebola transmission might be ongoing, an important question is: how will such a vaccination be perceived if a vaccinated person develops Ebola? Such a scenario is possible in people who contract Ebola virus before vaccination. If a person is infected with Ebola virus before vaccination, the vaccine might have a post-exposure prophylactic effect. However, how effective this prophylaxis might be is unknown.2 Moreover, if someone is infected more than 48 h before vaccination, the post-exposure prophylactic effect is likely to be insufficient, leading to possible development of Ebola after vaccination. This scenario is likely to result in serious issues relating to community trust and acceptance of an Ebola vaccine.3 How to exclude Ebola among people presenting with post-vaccination fever is also an issue.2

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The Case for Improved Diagnostic Tools to Control Ebola Virus Disease in West Africa and How to Get There

PLOS by Arlene C. Chua,Jane Cunningham,Francis Moussy, Mark D. Perkins,and Pierre Formenty      June 11 2015

 ...Since the identification of Ebola in Guinea in March 2013, rapid deployment of international mobile laboratories through WHO networks—Global Outbreak Alert and Response Network (GOARN) [2] and Emerging and Dangerous Pathogens Laboratory Network (EDPLN) [3]—has been vital to outbreak control operations. Deployable laboratories from multiple international organizations have been established near Ebola treatment centers (ETC) in Guinea, Liberia, and Sierra Leone....

However, several technical and social factors conspire to delay diagnosis, starting with weak surveillance systems and slow patient access to centralized ETCs. While the mean processing time is 5 hours (time difference from when samples are received in the laboratory to when they are tested), there is a marked difference in the time from when the samples are collected from suspected patients to the time they are received by the laboratory

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Bethlehem's Orasure gets government contract to develop quick Ebola test

LEIGH VALLEYLIVE  by Tony Rodin                             June 12, 2015

BETHLAHEM, PENNSYLVANIA  --OraSure Technologies Inc., a Bethlehem company that pioneered a quick test for determining HIV infection, has received a more than $10 million multiphase government contract to do the same for Ebola diagnosis, the company said Friday morning.

The company has developed a prototype device "that appears to deliver analytical performance similar to laboratory PCR tests when evaluated on stored samples from infected patients," the company said.

The three-year contract begins with a $1.8 million commitment and can add $8.6 million for clinical and regulatory activities, the company said.

The Ebola test will utilize the same OraQuick technology used in the company's rapid HIV and hepatitis C test kits, the company said.

Read complete story.
http://www.lehighvalleylive.com/bethlehem/index.ssf/2015/06/bethlehems_orasure_gets_govern.html

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International Ebola Recovery Conference Ending Ebola: “Get to Zero, Stay at Zero and Rebuild”

Congo Town, Freetown, Sierra Leone. Photo: Dylan Lowthian/UNDP

Image: Congo Town, Freetown, Sierra Leone. Photo: Dylan Lowthian/UNDP

africa.undp.org - May 9th, 2015

United Nations Secretary-General Ban Ki-moon will host an International Ebola Recovery Conference in July to ensure that the affected countries receive the resources and support they need to overcome the wider socio-economic consequences of the ongoing Ebola outbreak.

The conference at United Nations Headquarters in New York on 10 July 2015 will take place in cooperation with the Governments of Guinea, Liberia and Sierra Leone, together with other partners. 

With numbers of Ebola cases have dropped, the affected countries still need the support of the international community to get to zero cases, stay there, and to move forward on the road to recovery.

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