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Ebola pioneer, stem cell researcher honoured with Canada Gairdner Awards

CANADIAN PRESS                                                                                March 25, 2015
One of the co-discoverers of the Ebola virus and a leading Canadian stem cell researcher are among this year's winners of the prestigious Canada Gairdner Awards.

Dr. Peter Piot is the recipient of the Canada Gairdner Global Health Award, recognizing his work on the discovery of the Ebola virus in 1976 and his leadership in the global response to the HIV-AIDS epidemic.

Dr. Janet Rossant, chief of research at Toronto's Hospital for Sick Children, is the recipient of the 2015 Canada Gairdner Wightman Award, which honours a Canadian who has demonstrated outstanding leadership in medicine and medical science.

Five international scientists are also being honoured with Canada Gairdner Awards, two each from the United States and Japan and one from Switzerland....

Dr. Peter Piot won the 2015 Canada Gairdner Global Health Award in recognition of his work on the discovery of the Ebola virus in 1976 and his leadership in the global response to the HIV-AIDS epidemic. (David Azia/Associated Press)

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Ebola: Liberia's Johnson Sirleaf urges 'Marshall Plan'

BBC                                                                                                                      March 3, 2015

BRUSSELS --Liberian President Ellen Johnson Sirleaf has called for a "Marshall Plan" for the Ebola-affected countries of West Africa.

                             World leaders met in Brussels on Tuesday to discuss the fight against Ebola

She was referring to the massive US aid programme for Europe launched after World War Two.

Her comments came after Sierra Leone was immediately granted more than $80m (£52m) to help end the Ebola outbreak and recover from its effects.

The IMF has pledged a $187m financial aid package for Sierra Leone.

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http://www.bbc.com/news/world-africa-31705594

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Liberia’s President Urges U.S. to Continue Ebola Aid

NEW YORK TIMES  by Helene Cooper                     Feb. 27, 2015

WASHINGTON — President Ellen Johnson Sirleaf of Liberia on Friday urged the United States to maintain its assistance to her country as it continues to fight to recover from the Ebola outbreak, which began about one year ago.

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Mission Not Yet Accomplished --Editorial

EDITORIAL: NEW YORK TIMES                                       Feb. 17, 2015
President Obama has announced that almost all of the American troops sent to West Africa to help contain the Ebola epidemic will be withdrawn soon. That makes sense because they have largely completed the work they were sent to do. The next phase of the battle will rely on public health measures carried out by local and international health workers and experts.

Despite major gains, about 100 new cases are detected each week. It will take a concerted effort, backed financially by the United States and others, to drive that number down to zero....

The main task now facing public health workers is to find all people infected with Ebola and trace and isolate all their contacts to prevent passing the virus to others. The goal is to eradicate all traces of the virus from the afflicted countries. A well-trained work force will be essential to this task. As Mr. Obama warned last week, “Every case is an ember that if not contained can light a new fire.”

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http://www.nytimes.com/2015/02/16/opinion/mission-not-yet-accomplished.html

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Ebola: the race to find a cure

 In October, scientists set out to do something unprecedented – conduct a drugs trial during an epidemic to find a treatment for a lethal disease. Could they make history and change the way we deal with outbreaks?

THE GUARDIAN  by Sarah Boseley                           Feb, 17, 2015

In depth description of efforts by a group of Oxford University scientists to run field trials of drugs for use against Ebola.

" ...The little band of scientists had flown to Guinea on 16 October to do something that had never been successfully done before – set up a trial of experimental drugs against an infectious disease in the middle of an epidemic. Because the Ebola virus does not exist at low levels in any population, unless you run a properly conducted trial while the storm is raging, you will never have drugs that are proven to be effective. The Oxford team’s trial would not only aim to find a drug that worked against Ebola but also to establish a blueprint for the way drug trials would be run during outbreaks in the future. This did not just apply to fighting Ebola: if the scientists were successful, their trial would develop protocols for testing drugs for any epidemic, be it Sars or flu...."

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What Liberia needs from donors post-Ebola

DEVEX    by Molly Anders                                                                                                   Feb. 16, 2015

Interview with Liberian Assistant Minister of Health Tolbert Nyenswah about his vision for the development community’s role in a post-Ebola Liberia: 

" Every facet of our society was affected. From women and children to social protections, our economy and financial system; the GDP suffered hugely because of Ebola.
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Ebola in west Africa: learning the lessons

THE LANCET  by  Anna  Petherick  Volume 385, No. 9968, p591–592, 14 February 2015
The (West Africa) region has presented unforeseen challenges, and the three worst affected countries have put in place different response strategies. Anna Petherick reviews some of the lessons learned so far.

The early history of the ongoing Ebola outbreak in west Africa is a salutary statement about the lack of infectious disease surveillance capacity in one of the world's poorest regions....

Opportunities to contain the virus were lost soon after, largely because of a lack of trust between local communities and the officials and medical professionals trying to nip the epidemic in the bud.

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http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2815%2960075-7/fulltext

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Why Didn't Ebola Kill Me?

An ambulance transports the author to the Nebraska Medical Center in October. (Sait Serkan Gurbuz/Reuters)

THE ATLANTIC by Ashoka Mukpo                                                                          Feb. 12, 2015

Like the majority of patients taken to Western hospitals, I recovered from the disease—but health authorities are still struggling to figure out how to bring up the much-lower survival rate in West Africa.

...the 80-percent survival rate among patients who were evacuated to Western hospitals shattered the idea that an Ebola diagnosis spelled near-certain death. I know this all too well, as I’m one of those patients myself. In October, I contracted Ebola while covering the outbreak as a freelance journalist in Liberia. I was airlifted to a hospital in Nebraska, where aggressive treatment likely saved my life....
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http://www.theatlantic.com/health/archive/2015/02/why-didnt-ebola-kill-me/385335/

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UN: 10,000 US-supported civilians needed to fight Ebola

ASSOCIATED PRESS by Edith M. Leder                                                                          Feb. 11, 2015
UNITED NATIONS (AP) — The U.N. Ebola chief says U.S. troops being withdrawn from Liberia have done their job of building desperately needed treatment centers but that more than 10,000 civilians working in West Africa and supported by the United States are still essential to combating the deadly disease.

Dr. David Nabarro warned in an interview Wednesday with The Associated Press that the battle against Ebola is far from over, pointing to a disappointing rise in new cases last week in hardest-hit Liberia, Sierra Leone and Guinea.

He said civilians from the U.S., Britain, France and elsewhere are still needed to help with tracing Ebola victims' contacts, re-establishing health services and changing behavior in communities.

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http://news.yahoo.com/un-ebola-chief-10-000-us-civilians-needed-183453840.html;_ylt=AwrBJSCfs9xUf00Af7XQtDMD

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'Good virus' believed to help increase survival chances in Ebola and HIV infections

INTERNATIONAL BUSINESS NEWS by Jayalaksmi K      Feb. 2, 2015

A common virus that infects billions at some point of their lives is believed to deliver some protection against other deadlier viruses like HIV and Ebola.

David O'Connor, a pathology professor at the University of Wisconsin in Madison, found the genetic fingerprints of the virus GBV-C in the records of 13 samples of blood plasma from Ebola patients.

While six of the 13 people who were co-infected with Ebola and GBV-C died, seven survived.

Combined with earlier studies that have hinted persistent infection with the virus slowed disease progression in some HIV patients, researchers think the virus could be beneficial.

"We're very cautious about over-interpreting these results," O'Connor told NPR. He is now waiting to get a bigger sample, to see if there really is a strong connection between GBV-C infection and survival.
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