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WHO plans to speed development of Ebola rapid test

CENTER FOR INFECTIOUS DISEASE RESEARCH AND POLICY
By Lisa Schnirring                                               Nov.18, 2014

Quicker and simpler diagnostic tests for Ebola could go a long way in helping break chains of disease transmission in West Africa's outbreak region, the World Health Organization (WHO) said today, as it unveiled two new initiatives to expedite their development.

The WHO said it hopes new efforts—similar to those under way to test and deliver an Ebola vaccine—can compress the development of a rapid test in months instead of years.

A Navy worker extracts RNA from a patient sample at a Naval mobile lab in Liberia. US Army Africa

Standard reverse-transcriptase polymerase chain reaction (RT-PCR) tests used in mobile and other labs in the outbreak are very accurate when conducted by trained staff, but they require a full tube of blood, take 2 to 6 hours to get a result, and costs around $100 per test, the WHO said today in a statement....

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Queen Fears Ebola Push at Expense of Other Killer Diseases

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The Shifting Ebola Epidemic

NEW YORK TIMES                                                                                         Nov. 16, 2014

EDITORIAL

Recent gains in controlling the Ebola epidemic in West Africa have been encouraging, but they offer no reason for complacency. In Liberia, the hardest-hit country, the rate of new infections has declined in some areas, and several treatment units have been reporting empty beds for more than a month. But in adjacent Sierra Leone the number of new cases has shot upward, while in Guinea, where the epidemic started, the incidence of new cases appears to have stabilized over all, with growth in some districts and declines in others. All told, Ebola has infected more than 14,000 people in West Africa and killed more than 5,000 of them...

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Bats’ Link to Ebola Finally Solved

 

THE DAILY BEAST                                                                                                           Nov. 11, 2014
By Carfrie Arnold

A new paper outlines five steps required for a virus to ‘spill over’ from bats to humans. But don’t just blame the bats—deforestation and hunting are to blame, too.

These nocturnal fliers might do some good, but their association with night, rabies, and All Things Creepy means that, at best, we tolerate them. Adding to their negative aura is recent research showing that bats can be the source of infectious diseases like SARS and Ebola, as well as lesser-known pathogens like Hendra and Nipah virus.

It’s all too easy to blame bats for causing these human pandemics, including the most recent (and deadliest) Ebola outbreak. After all, these viruses hang out in bats in between outbreaks—trace any outbreak of these viruses back far enough and you will find a bat.

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Are we asking the wrong questions about Ebola?

BBC NEWS MAGAZINE                                            NOV. 11, 2014

By Ben Carter

The Ebola virus has killed about 5,000 people since March - but one scientist who is studying the statistics says this is not the best figure to consider if we really want to understand the current state of the outbreak and how to beat it.

 

 

A total of 4,960 people have died from Ebola this year according to statistics released by the World Health Organisation on 4 November. More than half of those cases - 2,766 - were in Liberia.

But this cumulative figure, which is widely reported, can only go one way - up. It gives no meaningful insight into how the outbreak has developed says Hans Rosling, professor of global health at the Karolinska Institute in Sweden....

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http://www.bbc.com/news/magazine-30011521

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Ebola: Online briefing now available to the public

 

 

DOCTORS WITHOUT BORDERS                                                                              Nov. 12, 2014

The international medical organisation Médecins Sans Frontières (MSF) or Doctors Without Borders has posted an online briefing on Ebola for aid workers involved in the battle against the haemorrhagic fever. This briefing package is now available to anyone wishing to gain a basic understanding of the virus and how it can be contained.

http://www.msf.org/article/ebola-online-briefing-now-available-public

View the briefing at
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Lawmakers question Obama's $6-billion request for Ebola funding

LOS ANGELES TIMES                                           Nov. 12, 2014
By Matt Hansen
Weighing President Obama’s request for billions of dollars in new funding to combat the Ebola virus, lawmakers on Wednesday pressed federal agencies to explain how the additional money would help in the fight against the disease.

Members of the Senate Appropriations Committee debated Obama’s request for $6.18 billion in additional funds to battle the virus, which has infected more than 13,000 people, mostly in West Africa...

Health and Human Services Secretary Sylvia Mathews Burwell and Homeland Security Secretary Jeh Johnson appear before the Senate Appropriations Committee during a hearing Tuesday in Washington over the government's response to Ebola. (Michael Reynolds / European Pressphoto Agency)

... the request faced skeptical lawmakers who questioned whether additional money would be well spent by a federal government that has struggled at times with containing the epidemic.

“Instead of an effective response, what we’ve witnessed from various agencies is confusing and at times contradictory plans,” Sen. Richard C. Shelby (R-Ala.) said.

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Ebola-carrying bats may be heroes as well as villains

REUTERS                                                                                  NOV. 2, 014

By Ben Hirschler

LONDON - Bats are living up to their frightening reputation in the world's worst Ebola outbreak as prime suspects for spreading the deadly virus to humans, but scientists believe they may also shed valuable light on fighting infection.

Fruit bats are seen for sale at a food market in Brazzavile, Republic of Congo, in this file photograph dated December 15, 2005. REUTERS/Jiro Ose/Files

Bats can carry more than 100 different viruses, including Ebola, rabies and severe acute respiratory syndrome (SARS), without becoming sick themselves.

While that makes them a fearsome reservoir of disease, especially in the forests of Africa where they migrate vast distances, it also opens the intriguing possibility that scientists might learn their trick in keeping killers like Ebola at bay.

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Assessing the Science of Ebola Transmission

THREE ARTICLES DESCRIBING DETAILS OF THE EBOLA VIRUS AND OTHER VIRUSES.
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Advances in microscopy have allowed scientists like Sriram Subramaniam and colleagues at the National Cancer Institute to look at the workings of tiny viruses. In this case, microscopy was used to illustrate the complex process in which human cells infected with HIV-1, green and blue, are linked to uninfected cells. Credit Illustration by Donald Bliss/N.I.H, from The Journal of Virology/American Society for Microbiology

The research on how the virus spreads is not as ambiguous as some have made it seem

THE ATLANTIC                                                                                                          Oct. 28, 2014

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