Exclusive: U.S. Ebola researchers plead for access to virus samples

A transmission electron micrograph shows Ebola virus particles in this undated handout image released by the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) in Fredrick, Maryland. Credit: Reuters/USAMRIID/Handout

Image: A transmission electron micrograph shows Ebola virus particles in this undated handout image released by the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) in Fredrick, Maryland. Credit: Reuters/USAMRIID/Handout

reuters.com - November 5th 2014 - Julie Steenhuysen

Scientists across the United States say they cannot obtain samples of Ebola, complicating efforts to understand how the virus is mutating and develop new drugs, vaccines and diagnostics.

The problems reflect growing caution by regulators and transport companies about handling Ebola as well as the limited resources of West African countries which are struggling to help thousands of infected citizens.

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Ban Ki-moon: The Ebola fight is far from over

WASHINGTON POST  OP-ED                                                                                      Nov. 9, 2014

By Ban Ki-moon, Secretary-General of the United Nations.

The Ebola outbreak is moving into a new phase that, in many ways, requires even greater attention and action than it has to this point. In addition to fears about the reach of the unforgiving virus and the spread of unfounded global panic, another concern has been added to the list: declaring “mission accomplished” too soon.

The rate of new Ebola cases shows encouraging signs of slowing in some of the hardest-hit parts of Liberia, Guinea and Sierra Leone — and that’s good news. The full-scale international strategy to attack Ebola through safe burials, treatment facilities and community mobilization is paying dividends.

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Homebound Filipino troops from Liberia Ebola-free

ASSOCIATED PRESS                                        NOV. 9. 2014

 MANILA, Philippines — The Philippine military said Sunday that 108 of its peacekeepers have tested negative for Ebola in Liberia, but that they will still be shipped to a small island in Manila Bay when they fly home this week for 21 more days of quarantine....

The Philippines has decided to halt the deployment of its troops to the West African nation amid the deadly Ebola outbreak there, ending more than a decade of peacekeeping work under the United Nations.

Read complete story
https://news.yahoo.com/homebound-filipinos-troops-liberia-ebola-free-055443426.html

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Morocco Insists on Delaying African Cup Over Ebola

ASSOCIATED PRESS                                   Nov. 8, 2014

REBAT-- Morocco is sticking to its demand to postpone the African Cup of Nations football tournament due to the outbreak of Ebola in West Africa, despite pressure from the Confederation of African Football.

A statement from the Ministry of Sports late Saturday said that because of the "spread of the deadly Ebola pandemic," Morocco was maintaining its call for delaying the tournament it is scheduled to host from Jan. 17-Feb. 8, to the following year.

The Confederation of African Football has repeatedly rejected calls to postpone the tournament and last Monday gave Morocco five days to agree to hold the tournament as scheduled or they would reassign it.

The body will meet again on Tuesday to make a final decision on whether the tournament will be delayed or assigned to another country.

Read complete story

http://abcnews.go.com/Sports/wireStory/morocco-insists-delaying-african-cup-ebola-26781383

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Ebola outbreak: Africa sets up $28.5m crisis fund

BBC                                                   Nov. 8 2014

Top African business leaders have established an emergency fund to help countries hit by the Ebola outbreak.

A pledging meeting in Addis Ababa, Ethiopia, raised $28.5m to deploy at least 1,000 health workers to Guinea, Sierra Leone and Liberia..... 

It is not clear why exactly the number of cases in Liberia has dipped - but it has been running an awareness campaign to advertise best health practices and install hand washing stations.

Speaking at the end of the Addis Abada meeting, African Union chairman Dlamini Zuma said the resources mobilised would be part of a longer term programme to deal with such outbreaks in the future.

The chairman of telecommunications giant Econet Wireless, Strive Masiyiwa, said that several companies had pledged money to the emergency fund - to be managed by the African Development Bank.

See complete story

http://www.bbc.com/news/world-africa-29967124

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Infection Secrets of Ebola Explained

By attacking the body's first responders, the virus cripples the immune system before it can mount an effective defense

Researchers often describe the battle between the Ebola virus and the humans it occasionally infects as a race—one that people win only if their immune systems manage to pull ahead before the virus destroys too many of their internal defenses. What they may not know is that the virus is a cheat.

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UN releases manual for safe Ebola burials

THE ASSOCIATED PRESS                                     NOV. 17, 2014

BERLIN  The World Health Organization has released a 17-page manual detailing how to safely bury people who have died from Ebola.

The U.N. agency said Friday the guidelines are part of an effort to reduce the likelihood of people contracting Ebola from corpses.

WHO Ebola expert Pierre Formenty says at least one in five infections occur during burials.

The guidelines give step-by-step advice to health workers for both Christian and Muslim burials.

See complete article
http://news.yahoo.com/un-releases-manual-safe-ebola-burials-154352654.html

See WHO manual

http://apps.who.int/iris/bitstream/10665/137379/1/WHO_EVD_GUIDANCE_Burials_14.2_eng.pdf?ua=1

http://www.who.int/csr/resources/publications/ebola/safe-burial-protocol/en/

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US Officials Unveil Plan to Test Ebola Drugs

NEW ORLEANS --The quest for an Ebola treatment is picking up speed. Federal officials have unveiled a plan to test multiple drugs at once, in an umbrella study with a single comparison group to give fast answers on what works.

"This is novel for us" and is an approach pioneered by cancer researchers, said Dr. Luciana Borio, head of the U.S. Food and Drug Administration's Ebola response. "We need to learn what helps and what hurts" and speed treatments to patients, she said.

She outlined the plan Wednesday at an American Society of Tropical Medicine and Hygiene conference in New Orleans....

Everyone in the umbrella study would get supportive care, such as intravenous fluids, then be assigned to receive one of several drugs or be in a comparison group. That's needed because without one, there's no way to know if any problems or deaths are from the drug or the disease, Cox said....

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New study sheds light on the importance of supportive care for Ebola patients

                                                                     Nov. 6, 2014

...a WHO-coordinated retrospective study, published in the New England Journal of Medicine, provides evidence that supportive care, especially rehydration and correction of metabolic abnormalities, may contribute to patient survival.

The study analysed clinical data on 37 confirmed Ebola patients admitted for treatment at hospitals in Conakry, Guinea’s capital and most densely populated city.

The cases occurred during the first month of West Africa’s first outbreak of Ebola virus disease. Fourteen of the patients were heath care workers. The majority (12) acquired their infection in a health care setting.

The majority (65%) of patients were male, countering assumptions that women, who are more likely to provide home care for patients and prepare bodies for funerals and burials, are more frequently exposed and infected.

To replace fluids lost through severe diarrhoea, 36 patients (97%) received oral rehydration solution. Additional intravenous fluid resuscitation was given to 28 (76%) patients.

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U.N. Ebola chief voices guarded optimism

ASSOCIATED PRESS                                   NOV. 7, 2014

UNITED NATIONS -- The U.N.'s Ebola chief said an extraordinary global response over the past month has made him hopeful the outbreak could end in 2015, though he cautioned that the fight to contain the disease is not even a quarter done.

"Until the last case of Ebola is under treatment, we have to stay on full alert," Dr. David Nabarro said Thursday in an interview with The Associated Press. "It's still bad."

Nabarro said a month ago that the number of Ebola cases was probably doubling every three-to-four weeks. He warned then that without a mass global mobilization, "the world will have to live with the Ebola virus forever" and that the response needed to be 20 times greater.

But in the past four weeks, the rate of Ebola infections seems to be slowing in some parts of West Africa, Nabarro said in the interview. In other hotspots, he said, it appears to be expanding the way it was a month ago.

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A Look at the Worst-Ever Ebola Epidemic by Numbers

An overview of the numbers of Ebola cases in Africa and elsewhere.
ASSOCIATED PRESS                                                 NOV. 17, 2014b
By Maria Cheng, AP Medical Writer
LONDON --As the biggest-ever outbreak of Ebola continues to ravage West Africa, here are a few key numbers to get a handle on the epidemic:

13,042 and 4,818:

Medical workers wearing protective equipment surround a simulated patient during a demonstration for media members on their training for working with possible Ebola patients, Thursday, Nov. 6, 2014, at Madigan Army Medical Center on Joint Base Lewis McChord, near Tacoma, Wash. Madigan providers and nurses have been training to perform clinical skills, including inserting IVs, obtaining blood samples for testing and conducting ultrasounds while dressed in powered air purifying respirators, impermeable suits and multiple layers of gloves. The clinically-focused exercises use realistic patient simulators that speak through microphones and can express simulated bodily fluids. (AP Photo/Elaine Thompson) Close The Associated Press

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Experimental Ebola drugs should not be withheld, WHO says

World Health Organisation doubts feasibility of placebo-controlled trials in west Africa, but FDA favours ‘gold standard’

THE GUARDIAN                                                                                                           Nov. 6, 2014
By Sarah Bosley

Scientists involved in trials of experimental drug treatments for the Ebola epidemic in west Africa should not be compelled to withhold them from some patients, says the World Health Organisation, despite objections from the US that it is the only way to be sure they work.

Vials of the experimental VSE-EBOV vaccine for Ebola. Photograph: Mathilde Missioneiro/AP

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China to build Ebola hospital in Liberia

THE GUARDIAN                                                                             NOV. 6, 2014
By Jonathan Kaiman                            

BEIJING -- China plans to build a 100-bed medical centre in Liberia to combat Ebola, officials announced on Thursday, after criticism that the country is not doing enough to fight the disease.

 

 Chinese medical staff receiving an Ebola training session in Beijing. The size of China's aid response to the outbreak has     been criticised. Photograph: AFP/Getty Images

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Ebola crisis draining development budgets in West Africa, study finds

UNITED NATIONS DEVELOPMENT PROGRAMME                                              Nov. 5, 2014

New York  -- The Ebola outbreak in West Africa is impairing the ability of governments to raise revenues, increasing their exposure to domestic and foreign debts and may make them more dependent on aid, according to the latest study (PDF) on the socio-economic impact of the crisis carried out by the UN development agency.

Investments in kick-starting economies and long-term development urgently needed

“We need to make sure that the Ebola outbreak does not lead to socio-economic collapse,” said Abdoulaye Mar Dieye, the Director of the Regional Bureau for Africa at the United Nations Development Programme (UNDP). “This crisis is already taking a toll on budgets and reducing the governments’ policy leeway to make much-needed investments in critical areas such as health and education for their citizens.” He added that the effects of the Ebola crisis will last long after the epidemic is brought under control.

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How Guinea Found the Best Way to Survive Ebola

TIME MAGAZINE                                         Nov. 5, 2014

by Alice Park

As the world waits for new treatrments and a vaccine. doctors in Guinea have found the best way to help patients survive Ebola.

... from the tragic illness and mortality emerge some important lessons from the region.The latest, published in the New England Journal of Medicine, details the cases that first appeared in Guinea’s capital city of Conakry between March and April. Unlike in other parts of the region, where the mortality rate from Ebola averages around 60% to 70%, in Conakry it has remained around 43%.

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