Ebola still spreading in western Sierra Leone, Guinea's forest: U.N

REUTERS    By Stephanie Nebehay                                                                                 Dec. 9, 2014
GENEVA --More foreign health workers are needed to help tackle the Ebola epidemic, which is spreading quickly in western Sierra Leone and deep in the forested interior of Guinea, a senior U.N. official said on Tuesday.

A woman walks pass an Ebola virus awareness campaign poster in Monrovia, December 8, 2014. Credit: Reuters/James Giahyue

The death toll from the Ebola outbreak in West Africa has risen to 6,331 in the three worst hit countries, with Sierra Leone overtaking Liberia as the country with the highest number of cases, the World Health Organization says.

"We know the outbreak is still flaming strongly in western Sierra Leone and some parts of the interior of Guinea. We can't rest, we have to still push on," said David Nabarro, the U.N. Special Envoy on Ebola.

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U.S. agency offers legal immunity to Ebola vaccine makers

REUTERS                                                                                                                    Dec. 9, 2014

CHICAGO -- The U.S. Department of Health and Human Services on Tuesday offered liability protections to drugmakers rushing to develop Ebola vaccines and urged other countries to follow suit.

Health and Human Services (HHS) Secretary Sylvia Burwell made the announcement as part of the Public Readiness and Emergency Preparedness (PREP) Act in a move aimed at encouraging the development and availability of experimental Ebola vaccines.

The declaration provides immunity under U.S. law against legal claims related to the manufacturing, testing, development, distribution, and administration of three vaccines for the Ebola virus. However, it does not provide immunity for a claim brought in a court outside the United States...

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http://www.reuters.com/article/2014/12/09/us-health-ebola-vaccine-idUSKBN0JN1S920141209

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Undiagnosed Acute Viral Febrile Illnesses, Sierra Leone

wwwnc.cdc.gov/eid

Schoepp RJ, Rossi CA, Khan SH, Goba A, Fair JN. Undiagnosed acute viral febrile illnesses, Sierra Leone. Emerg Infect Dis [Internet]. 2014 Jul [date cited]. http://dx.doi.org/10.3201/eid2007.131265

DOI: 10.3201/eid2007.131265

CLICK HERE - RESEARCH - Undiagnosed Acute Viral Febrile Illnesses, Sierra Leone

Table of Contents – Volume 20, Number 7—July 2014

Abstract

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VIDEO - Council on Foreign Relations - Ebola Update: Assessment From Africa

Archived Video - Watch the meeting held on Tuesday, December 9, 2014, from 1:00 to 2:00 p.m. (ET).

Speakers: Nancy A. Aossey, President and Chief Executive Officer, International Medical Corps

Laurie Garrett, Senior Fellow for Global Health, Council on Foreign Relations; Author, Ebola: Story of an Outbreak

David Nabarro, Special Envoy on Ebola, United Nations

Presider: Richard E. Besser, Chief Health and Medical Editor, ABC News

Experts recently returned from trips to West Africa with medical teams operating Ebola-treatment units there discuss the situation on the ground and developments in the international response to the crisis.

CLICK HERE - Council on Foreign Relations - Ebola Update: Assessment From Africa

CLICK HERE - YouTube - Council on Foreign Relations - Ebola Update: Assessment From Africa

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Surviving Ebola

      

Decontee Davis: She won her battle with Ebola. Her 5-year-old son, though, paid a price. She didn’t want other kids to suffer the same way, so she embarked on a difficult new job.

washingtonpost.com

Decontee Davis, 23, works at a child-care center, where any of the 13 children could be coming down with Ebola.  All are from homes where parents or guardians have been taken away to treatment centers or died of Ebola, and now the youngsters must be monitored for 21 days to determine whether they are infected as well.

The job falls to a staff of 10, all survivors of Ebola like Davis, who watch them 24 hours a day.

(READ COMPLETE ARTICLE)

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Rapid Ebola test is focus of NIH grant to Rutgers scientist

REPORTS Of RESEARCH ON TWO METHODS OF RAPID TESTING FOR EBOLA

(Two items, scroll down)

MEDICAL PRESS                                                                                     Dec. 8, 2014

Rutgers researcher David Alland, working with the California biotechnology company Cepheid, has received a grant of nearly $640,000 from the National Institutes of Health to develop a rapid test to diagnose Ebola as well as other viruses that can cause symptoms similar to Ebola.

Researchers will adapt this cartridge, now used worldwide for tuberculosis screenings, to collect and test samples from potential Ebola patients. Credit: John Emerson

Alland, a professor of medicine and associate dean for clinical research at Rutgers New Jersey Medical School and the principal investigator of the project, says would be able to take the test to small villages and other remote locations where the spread of Ebola has been especially rampant and diagnose patients where they live...

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With Ebola Cases Down, Officials Worry Liberians Aren't Worried Enough

NATIONAL PUBLIC RADIO  by OFEIBEA QUIST-ARCTON                                          Dec. 8, 2014

MONROVIA -- Treatment units in Liberia stand nearly empty, but a dozen or so Ebola cases still appear each day, with clusters in Monrovia and rural areas. The CDC's chief there wants the nation to stay alert.

Interview with Kevin De Cock, the doctor leading the Ebola response effort in Liberia for the Centers for Disease Control and Prevention. He warns that the new enemy in the fight against the virus may be people letting down their guard.

Read rest of interview.

http://www.npr.org/2014/12/08/369276253/with-ebola-cases-down-officials-worry-liberians-arent-worried-enough

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In Ebola Outbreak, Bad Data Adds Another Problem

ASSOCIATED PRESS -By MARIA CHENG and SARAH DiLORENZO Dec. 14, 2014

LONDON--As health officials struggle to contain the world's biggest-ever Ebola outbreak, their efforts are being complicated by another problem: bad data.

Having accurate numbers about an outbreak is essential not only to provide a realistic picture of the epidemic, but to determine effective control strategies. Dr. Bruce Aylward, who is leading the World Health Organization's Ebola response, said it's crucial to track every single Ebola patient in West Africa to stop the outbreak and that serious gaps remain in their data.

"As we move into the stage of hunting down the virus instead of just slowing the exponential growth, having good data is going to be at the heart of this," Aylward said. "We are not there yet and this is something we definitely need to fix."

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An Ebola Doctor’s Return From the Edge of Death

Detailed description of one Doctor’s Story of Fighting Back From Ebola’s Deadly Grip

NEW YORK TIMES by Denise Grady                                Dec. 8, 2014

Dr. Ian Crozier, 44, contracted Ebola in Sierra Leone while treating patients. He was evacuated to Atlanta on Sept. 9 and had an agonizing illness, with 40 days in the hospital and dark stretches when his doctors and his family feared he might sustain brain damage or die. His identity was kept secret at his request, to protect his family’s privacy.

 

Now, for the first time, he is speaking out. His reason, he said, is to thank Emory for the extraordinary care he received, and to draw attention to the continuing epidemic.

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How ‘phenomenal’ staff in Nigeria cut Ebola fatality rate in half

THE TORONTO GLOBE AND MAIL by Kelly Grant                Dec.7, 2014

When the World Health Organization declared Nigeria officially Ebola-free in October, most of the fanfare centred on how Africa’s most populous country had managed to keep the virus from spreading.

But there was another, less heralded aspect of Nigeria’s success story that a Canadian doctor and her colleagues wanted to explore in more depth: How had 12 of Nigeria’s 20 Ebola patients beaten the virus?

The hospitals in Nigeria weren’t maybe to the standards of a Western hospital in terms of equipment, but the staff were phenomenal. They managed to get a very high survival rate,” said Eilish Cleary, a New Brunswick chief medical officer of health who travelled to Nigeria to provide epidemiological support to the World Health Organization during the outbreak. “Case fatality rate for Ebola can be up to 70 to 90 per cent. In Nigeria, it was 40 per cent.”

Dr. Cleary conducted detailed, videotaped interviews with six of the Nigerian patients to learn more about their treatment and recovery. The key to their survival seemed to be guzzling a stunning amount of water with oral rehydration solution [ORS] to fend off the cascade of internal failures typically caused by the virus.

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10th Sierra Leonean Doctor Dies From Ebola

FREETOWN, Sierra Leone --Another Sierra Leonean doctor has died from Ebola, the 10th to succumb to the disease, a health official said Sunday.

Dr. Aiah Solomon Konoyeima died Saturday, according to Chief Medical Officer Dr. Brima Kargbo. His death came a day after two other doctors died from Ebola, emphasizing the tremendous toll the disease has taken on health care workers.

Konoyeima worked at a children's hospital in the capital and tested positive for Ebola about two weeks ago. He was treated at the Hastings Ebola Treatment Center, which is staffed exclusively by Sierra Leonean medical personnel, as compared to many other treatment units, which are run by international organizations or employ some foreign staff.

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http://abcnews.go.com/Health/wireStory/10th-sierra-leonean-doctor-dies-ebola-27424222

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Cuban Ebola patient recovers after treatment in Geneva

REUTERS                                                                                                                                      Dec. 2014
                   
GENEVA-- Cuban doctor who received experimental treatment for Ebola in a Geneva hospital has made a full recovery and left Switzerland to be reunited with his family, the hospital said on Saturday.

Felix Baez, 43, was one of 256 Cuban doctors and nurses who went to West Africa to treat patients from the worst outbreak of the virus on record...

Soon after arriving in Geneva, Baez received the Canadian experimental treatment ZMab, a precursor to the Ebola drug ZMapp, which has been used to treat several U.S. patients...

A hospital spokeswoman said he received both ZMab and the untested flu drug favipiravir, made by Japan's Fujifilm, which the WHO has included on a list of potential Ebola treatments

Read complete story.
http://www.reuters.com/article/2014/12/06/us-health-ebola-cuba-idUSKBN0JK0BN20141206

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What Ebola can teach us about a new bubonic plague outbreak in Africa

THE WEEK -- by S.E. Smith                                                                                                     Dec. 5, 2014
While West Africa battles Ebola, another outbreak is striking just across the continent. In Madagascar, cases of plague are erupting in the small village of Mandritsara and the disease is spreading to neighboring communities. The two outbreaks are related by more than simple surface similarities, though. In fact, fighting the first has provided an invaluable blueprint for containing the second.West Africa's Ebola outbreak could inform responders to Madagascar's plague cases.

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Ebola in Graphics: The toll of a tragedy

THE ECONOMIST                                                                                                      Dec. 4, 2014

THE first reported case in the Ebola outbreak ravaging west Africa dates back to December 2013, in Guéckédou, a forested area of Guinea near the border with Liberia and Sierra Leone. Travellers took it across the border: by late March, Liberia had reported eight suspected cases and Sierra Leone six. By the end of June 759 people had been infected and 467 people had died from the disease, making this the worst ever Ebola outbreak. The numbers keep climbing. As of November 30th, 17,145 cases and 6,070 deaths had been reported worldwide, the vast majority of them in these same three countries. Many suspect these estimates are badly undercooked.

Read complete posting
http://www.economist.com/blogs/graphicdetail/2014/12/ebola-graphics

Link to an interactive map of the virus's current global reach:

http://www.economist.com/blogs/graphicdetail/2014/12/interactive-ebola-map

 

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Doctors Try Survivors’ Blood to Treat Ebola

Clinical Trials Are Being Launched in Africa but Face Challenges in Designing Ethical Studies, Compensating Donors

WALL STREET JOURNAL                                                                                                    Dec. 5, 2014
by Betsy McKay in Atlanta, David Gauthier-Villars in Conakry, Guinea, and Patrick McGroarty in Monrovia, Liberia

...Nearly a year after Ebola began spreading in West Africa, and with a proven drug or vaccine still far off, researchers are launching clinical trials on a product at hand: the blood of survivors.

 They want to determine whether so-called convalescent plasma or serum, chock full of antibodies, can help fight off the disease. But they face a number of complexities in carrying out the trials, including persuading survivors to participate....

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