MEDSCAPE MEDICAL NEWS by Larry Hand                                                                        Dec. 9, 2014

Airport exit screening in West Africa and entry screening in the United States have identified few persons potentially infected with Ebola virus, according to an article published online December 9 in the Centers for Disease Control and Prevention (CDC) publication Morbidity and Mortality Weekly Report.

 Number of travelers arriving from Guinea, Liberia, and Sierra Leone who were screened for Ebola at US airports, by state and county of destination (October 11 - November 10, 2014). Source: CDC

Of 80,000 travelers who have departed from West Africa since Ebola-specific screening began, 1993 people have been screened on arrival at one of five US airports. Of those, 86 passengers were referred to the CDC public health officers; only seven have shown symptoms and been referred for evaluation. None eventually wound up with an Ebola diagnosis.

NBC NEWS --  by Maggie Fox                                                                                            Dec. 9, 2014

Health care workers have more than 100 times the risk of catching Ebola in Sierra Leone as the general public there does, according to a new report.

And it's not necessarily down to failed protective measures in hospitals. Health care workers form their own community, and when one gets sick or dies, he or she can infect fellow medics, the report finds.

The World Health Organization has been saying that health care workers such as doctors and nurses are at special risk of Ebola. It says 622 health-care workers have been infected and 346 of them have died in all the affected countries.

Dr. Peter Kilmarx of the U.S. Centers for Disease Control and Prevention, who led an investigation into the high infection rate in Sierra Leone...said  "We think of health care worker infections as a failure of personal protective equipment.,"But there are so many different ways that they are exposed there."

A few months ago the U.S. Centers for Disease Control and Prevention predicted that up to 1.4 million people in Liberia and Sierra Leone could become infected with Ebola by mid-January. In a recent address to the Senate, CDC director Tom Frieden said that worst-case scenario would not pan out.

That is partly because health care workers in the Ebola hot zone are engaged in a battle to contain the epidemic. It is also because of assumptions about human and viral behavior that are built into the mathematical models used to predict the spread of infectious diseases. Assumptions are inherent in these models. “You take islands of data from different places and build bridges of assumptions that link up all these islands,” says Martin Meltzer, senior health economist at the CDC. Meltzer’s model, which predicted the 1.4 million infections in Liberia and Sierra Leone, worked on the assumption that things would not improve. “Our forecasts are based on the idea that nothing will change,” he says.

REUTERS    By Stephanie Nebehay                                                                                 Dec. 9, 2014
GENEVA --More foreign health workers are needed to help tackle the Ebola epidemic, which is spreading quickly in western Sierra Leone and deep in the forested interior of Guinea, a senior U.N. official said on Tuesday.

The death toll from the Ebola outbreak in West Africa has risen to 6,331 in the three worst hit countries, with Sierra Leone overtaking Liberia as the country with the highest number of cases, the World Health Organization says.

"We know the outbreak is still flaming strongly in western Sierra Leone and some parts of the interior of Guinea. We can't rest, we have to still push on," said David Nabarro, the U.N. Special Envoy on Ebola.

REUTERS                                                                                                                    Dec. 9, 2014

CHICAGO -- The U.S. Department of Health and Human Services on Tuesday offered liability protections to drugmakers rushing to develop Ebola vaccines and urged other countries to follow suit.

Health and Human Services (HHS) Secretary Sylvia Burwell made the announcement as part of the Public Readiness and Emergency Preparedness (PREP) Act in a move aimed at encouraging the development and availability of experimental Ebola vaccines.

The declaration provides immunity under U.S. law against legal claims related to the manufacturing, testing, development, distribution, and administration of three vaccines for the Ebola virus. However, it does not provide immunity for a claim brought in a court outside the United States...

Read full story

http://www.reuters.com/article/2014/12/09/us-health-ebola-vaccine-idUSKBN0JN1S920141209

wwwnc.cdc.gov/eid

Schoepp RJ, Rossi CA, Khan SH, Goba A, Fair JN. Undiagnosed acute viral febrile illnesses, Sierra Leone. Emerg Infect Dis [Internet]. 2014 Jul [date cited]. http://dx.doi.org/10.3201/eid2007.131265

DOI: 10.3201/eid2007.131265

CLICK HERE - RESEARCH - Undiagnosed Acute Viral Febrile Illnesses, Sierra Leone

Table of Contents – Volume 20, Number 7—July 2014

Abstract

Archived Video - Watch the meeting held on Tuesday, December 9, 2014, from 1:00 to 2:00 p.m. (ET).

Speakers: Nancy A. Aossey, President and Chief Executive Officer, International Medical Corps

Laurie Garrett, Senior Fellow for Global Health, Council on Foreign Relations; Author, Ebola: Story of an Outbreak

David Nabarro, Special Envoy on Ebola, United Nations

Presider: Richard E. Besser, Chief Health and Medical Editor, ABC News

Experts recently returned from trips to West Africa with medical teams operating Ebola-treatment units there discuss the situation on the ground and developments in the international response to the crisis.

CLICK HERE - Council on Foreign Relations - Ebola Update: Assessment From Africa

CLICK HERE - YouTube - Council on Foreign Relations - Ebola Update: Assessment From Africa

Decontee Davis: She won her battle with Ebola. Her 5-year-old son, though, paid a price. She didn’t want other kids to suffer the same way, so she embarked on a difficult new job.

washingtonpost.com

Decontee Davis, 23, works at a child-care center, where any of the 13 children could be coming down with Ebola.  All are from homes where parents or guardians have been taken away to treatment centers or died of Ebola, and now the youngsters must be monitored for 21 days to determine whether they are infected as well.

The job falls to a staff of 10, all survivors of Ebola like Davis, who watch them 24 hours a day.

(READ COMPLETE ARTICLE)

REPORTS Of RESEARCH ON TWO METHODS OF RAPID TESTING FOR EBOLA

(Two items, scroll down)

MEDICAL PRESS                                                                                     Dec. 8, 2014

Rutgers researcher David Alland, working with the California biotechnology company Cepheid, has received a grant of nearly $640,000 from the National Institutes of Health to develop a rapid test to diagnose Ebola as well as other viruses that can cause symptoms similar to Ebola.

Researchers will adapt this cartridge, now used worldwide for tuberculosis screenings, to collect and test samples from potential Ebola patients. Credit: John Emerson

Alland, a professor of medicine and associate dean for clinical research at Rutgers New Jersey Medical School and the principal investigator of the project, says health workers would be able to take the test to small villages and other remote locations where the spread of Ebola has been especially rampant and diagnose patients where they live...

NATIONAL PUBLIC RADIO  by OFEIBEA QUIST-ARCTON                                          Dec. 8, 2014

MONROVIA -- Treatment units in Liberia stand nearly empty, but a dozen or so Ebola cases still appear each day, with clusters in Monrovia and rural areas. The CDC's chief there wants the nation to stay alert.

Interview with Kevin De Cock, the doctor leading the Ebola response effort in Liberia for the Centers for Disease Control and Prevention. He warns that the new enemy in the fight against the virus may be people letting down their guard.

Read rest of interview.

http://www.npr.org/2014/12/08/369276253/with-ebola-cases-down-officials-worry-liberians-arent-worried-enough

ASSOCIATED PRESS -By MARIA CHENG and SARAH DiLORENZO Dec. 14, 2014

LONDON--As health officials struggle to contain the world's biggest-ever Ebola outbreak, their efforts are being complicated by another problem: bad data.

Having accurate numbers about an outbreak is essential not only to provide a realistic picture of the epidemic, but to determine effective control strategies. Dr. Bruce Aylward, who is leading the World Health Organization's Ebola response, said it's crucial to track every single Ebola patient in West Africa to stop the outbreak and that serious gaps remain in their data.

"As we move into the stage of hunting down the virus instead of just slowing the exponential growth, having good data is going to be at the heart of this," Aylward said. "We are not there yet and this is something we definitely need to fix."

Detailed description of one Doctor’s Story of Fighting Back From Ebola’s Deadly Grip

NEW YORK TIMES by Denise Grady                                Dec. 8, 2014

THE TORONTO GLOBE AND MAIL by Kelly Grant                Dec.7, 2014

When the World Health Organization declared Nigeria officially Ebola-free in October, most of the fanfare centred on how Africa’s most populous country had managed to keep the virus from spreading.

But there was another, less heralded aspect of Nigeria’s success story that a Canadian doctor and her colleagues wanted to explore in more depth: How had 12 of Nigeria’s 20 Ebola patients beaten the virus?

The hospitals in Nigeria weren’t maybe to the standards of a Western hospital in terms of equipment, but the staff were phenomenal. They managed to get a very high survival rate,” said Eilish Cleary, a New Brunswick chief medical officer of health who travelled to Nigeria to provide epidemiological support to the World Health Organization during the outbreak. “Case fatality rate for Ebola can be up to 70 to 90 per cent. In Nigeria, it was 40 per cent.”

Dr. Cleary conducted detailed, videotaped interviews with six of the Nigerian patients to learn more about their treatment and recovery. The key to their survival seemed to be guzzling a stunning amount of water with oral rehydration solution [ORS] to fend off the cascade of internal failures typically caused by the virus.

FREETOWN, Sierra Leone --Another Sierra Leonean doctor has died from Ebola, the 10th to succumb to the disease, a health official said Sunday.

Dr. Aiah Solomon Konoyeima died Saturday, according to Chief Medical Officer Dr. Brima Kargbo. His death came a day after two other doctors died from Ebola, emphasizing the tremendous toll the disease has taken on health care workers.

Konoyeima worked at a children's hospital in the capital and tested positive for Ebola about two weeks ago. He was treated at the Hastings Ebola Treatment Center, which is staffed exclusively by Sierra Leonean medical personnel, as compared to many other treatment units, which are run by international organizations or employ some foreign staff.

Read complete story
http://abcnews.go.com/Health/wireStory/10th-sierra-leonean-doctor-dies-ebola-27424222

REUTERS                                                                                                                                      Dec. 2014
                   
GENEVA-- Cuban doctor who received experimental treatment for Ebola in a Geneva hospital has made a full recovery and left Switzerland to be reunited with his family, the hospital said on Saturday.

Felix Baez, 43, was one of 256 Cuban doctors and nurses who went to West Africa to treat patients from the worst outbreak of the virus on record...

Soon after arriving in Geneva, Baez received the Canadian experimental treatment ZMab, a precursor to the Ebola drug ZMapp, which has been used to treat several U.S. patients...

A hospital spokeswoman said he received both ZMab and the untested flu drug favipiravir, made by Japan's Fujifilm, which the WHO has included on a list of potential Ebola treatments

Read complete story.
http://www.reuters.com/article/2014/12/06/us-health-ebola-cuba-idUSKBN0JK0BN20141206