A Tale of Two Outbreaks: Why Congo Conquered Ebola

NBC NEWS    By Maggie Fox                                                                              Nov. 24, 2014

Two outbreaks, two entirely different outcomes. The World Health Organization has declared an outbreak of Ebola over in the Democratic Republic of Congo after just 66 cases and 49 deaths. It lasted three months.

Yet the epidemic in Liberia, Sierra Leone and Guinea’s been going for nine months, with more than 15,000 cases, 5,000 deaths and no end in sight.

What’s the difference? Experts say experience matters — it was the seventh outbreak in the former Zaire. But equally important is the fact that the village where it started was extremely remote, and the country has a rudimentary system of healthcare workers who know to look out for Ebola.

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http://www.nbcnews.com/storyline/ebola-virus-outbreak/tale-two-outbreaks-why-congo-conquered-ebola-n253911

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Notable Absence of New Ebola Quarantines at New York Area Airports

NEW YORK TIMES    By Anemona Hartocollis                                                          NOV. 24, 2014

NEW YORK   ...since Kaci Hickox, a nurse, flew into Newark’s airport on Oct. 24 and was kept at a hospital for three days, no one else has been caught up in the quarantine dragnet at the New York and New Jersey airports.

The absence of quarantines is striking, not only because both governors emphatically defended the policy as a necessary precaution, but also because most people returning from Ebola-stricken countries arrive in the United States through Kennedy and Newark Liberty International Airports.

...New York and New Jersey officials say no one coming through the two airports since Ms. Hickox has reported direct contact with Ebola patients.

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The US Is Stockpiling Ebola Survivors’ Plasma to Treat Future Patients

                                                                                                    Getty Images

WIRED                 BY Katie M. Palmer                                                    Nov. 24, 214

The FDA announced Friday that it would start developing a stockpile of blood plasma from Ebola survivors, treated with a pathogen inactivation system that’s never been used before in the United States.

So far, the US has had some amazing success in curing Ebola, possibly thanks to experimental plasma treatments. Drawn from survivors, the stuff comes enriched in antibodies that could help to fight off the disease—but it also has the potential to carry other diseases, like malaria, that are common in west Africa where Ebola is raging. The new system will kill off any extra contaminants that may be lurking in this potentially live-saving serum.

It’s the same one, Cerus Corporation’s Intercept system, that will be used in a Gates Foundation-funded study of Ebola treatments in West Africa. The pathogen-killing molecule at the heart of the system is amotosalen, part of a class of three-ringed molecules called psoralens....

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Italian Doctor With Ebola Returning for Treatment

ASSOCIATED PRESS                                                      Nov. 24, 2014

MILAN --An Italian doctor who has been working in Sierra Leone has tested positive for the Ebola virus and is being transferred to Rome for treatment, the health ministry said Monday. It is Italy's first confirmed case of Ebola.

The doctor, who was not identified and who works for the non-governmental organization Emergency, is scheduled to arrive overnight in Italy for treatment at the Lazzaro Spallanzani National Institute for Infectious Diseases in Rome.

Emergency, which is operating a center for Ebola treatment in Lakka, Sierra Leone, said in statement that the doctor was in good condition, and that its staff in the country is following protocols aimed at avoiding contagion. "Nonetheless, no health intervention of such a serious epidemic can be considered completely without risks," Emergency said.

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http://abcnews.go.com/Health/wireStory/italian-doctor-ebola-returning-treatment-27130191

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Ebola Mappers Track Epidemic in Real Time 
 
 


NBC NEWS       By Nikita Japra                                                                                     Nov. 23, 2014
In a darkened Boston conference room, staring at projections from a laptop, John Brownstein is far from the front lines of the fight against Ebola. But the epidemiologist’s work may help change the course of the epidemic.

The disease forecaster and his team are combing through news reports, tweets and Facebook posts to anticipate the disease’s next move — and help those on the ground head it off before the crisis grows....

Brownstein’s HealthMap scours social media and local news from around the globe to locate potential hot spots and display them in an interactive map. In the past, HealthMap has spotted outbreaks ranging from H1N1 swine flu to Dengue fever. Today, the team is building interactive maps that can guide the response to the worst Ebola outbreak ever recorded.

While official numbers from government agencies can take precious time to confirm, Brownstein’s team looks to more immediate, unconventional sources to help target the right communities at the right time.

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The suit designed to come between NHS Ebola workers and death

THE TELEGRAPH     By Rosa  Silverman                                                                                      Nov.23, 2014

With its domed helmet, protective outer apron and thick boots, this is the kit National Health Service medics are depending on to save their lives as they fight Ebola in Africa.

More than 30 volunteers from the UK arrived in Sierra Leone today, prepared to join the effort to combat the deadly virus.

The medics, who came from across Britain and flew from London’s Heathrow airport on Saturday, were the first batch of NHS volunteers to be deployed by the Government after more than a thousand came forward to offer their services.

Among them are GPs, nurses, psychiatrists and emergency medicine consultants, all of whom will work in treatment centres built by British Army Royal Engineers and funded by the Department for International Development.

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War against Ebola in West Africa remains a tough fight

USA TODAY                       By Greg Zoraya                                                                                 Nov. 23, 2014

MONROVIA, Liberia — A snapshot of the Ebola epidemic raging across West Africa shows a wildfire of infections only slightly contained.

While cases have been on the decline in Liberia, the outbreak is worsening in neighboring countries, where basic Ebola-fighting tools are impractical.

Identifying the infected and those they've touched, and isolating them to break the transmission chain are all but impossible in Sierra Leone's capital of Freetown as well as the jungles of Guinea, says Jordan Tappero, the Centers for Disease Control and Prevention's second-in-command for the regional response...

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A journey through West Africa's Ebola stricken countries

BBC                                                               Nov. 23, 2014

The BBC's Tulip Mazumdar has been on a trip across two West African nations affected by Ebola to see how the authorities are dealing with the virus.

Soldiers and workers use temperature guns at the checkpoints

Tulip's journey began in Freetown, the capital of Sierra Leone and took her 260km (161.5 miles) through some of the areas badly hit by Ebola to Conakry, the capital of Guinea.

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http://www.bbc.com/news/health-30166565

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Probing Ebola's Deadly Inflammatory Effect

      

New research suggests that Ebola's deadly inflammatory effects may be caused by the result of protein shedding by infected cells. (Victor Volchkov / PLOS Pathogens)

CLICK HERE - RESEARCH - PLOS Pathogens - Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability

latimes.com - by Monte Morin - November 20, 2014

New research suggests that the massive and destructive inflammation that characterizes Ebola virus disease may be caused by the release of foreign proteins from infected cells.

Although Ebola is infamous for causing bleeding in some of its victims, doctors say the vast majority of deaths are the result of organ failure and shock brought on by the uncontrolled release of cytokines, compounds that cells use to communicate with one another and control immune response. . .

. . . In a paper published Thursday in Plos Pathogens, researchers at the Claude Bernard University of Lyon, in France, argued that glycoprotein shedding by infected cells may explain the immune system's damaging response.

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Ebola crisis now 'stable' in Guinea, WHO says

BBC                                                                                                                          Nov. 22, 2014

The Ebola outbreak is now "relatively stable" in Guinea, where the latest crisis began, the World Health Organization says.

There were still some flare ups in the south-east, but things were improving in other prefectures, WHO co-ordinator Dr Guenael Rodier told the BBC....

Ebola patients are taken to dedicated treatment centres across Guinea

"When you look in more detail, you see that it's still quite active in the Guinea forest area [in] the south of the country," Dr Rodier said.

However, he added that the situation was "actually improving in a number of prefectures, especially Conakry", where there was a fairly good understanding of how the disease was spreading.

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http://www.bbc.com/news/world-africa-30160659

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An Ebola Clinic Figures Out A Way To Start Beating The Odds

NATIONAL PUBLIC RADIO                                                                                                        Nov. 21, 2014
by Nurith Aizenman

FREETOWN, Sierra Leone

Description of how the Hastings Ebola Treatment Center in Freetown, Sierra Leone is having success by having experienced nurses useIV's to counter the dehydration of Ebola patients.

Health workers are disinfected with a chlorine solution after treating patients at the Hastings Ebola Treatment Center in Freetown.

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http://www.npr.org/blogs/goatsandsoda/2014/11/21/365715575/an-ebola-clinic-figures-out-a-way-to-start-beating-the-odds

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UN security council criticises discrimination against those from Ebola-hit regions

THE GUARDIAN                                                    Nov. 21, 2014
THE UNITED NATIONS --The UN security council has criticized travel bans against nationals from Ebola-hit countries.

Last month the Australian immigration minster, Scott Morrison, announced Australia would stop granting temporary visas to visitors from west Africa. The security council statement criticised such blanket bans and urged countries to maintain links with affected countries.

“The security council expresses its continued concern about the detrimental effect of the isolation of the affected countries as a result of trade and travel restrictions imposed on and to the affected countries as well as acts of discrimination against the nationals of Guinea, Liberia, Mali and Sierra Leone,” said Julia Bishop, the Australian foreign mniister who was presiding over the session Thursday.

The council statement also described the Ebola outbreeak in Africa as "a threat to international peace and security..."

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Officials Revise Goals on Containing Ebola After Signs of Wider Exposure in Mali

NEW YORK TIMES                                     Nov. 21, 2014
By and

The leaders of the United Nations and the World Health Organization expressed renewed alarm on Friday about Ebola’s tenacity in Africa and, in particular, its potential to ravage a fourth country, Mali, where they said hundreds of people had been exposed to an infected cleric who died last month.

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Ebola Deaths Near 5,500 As Virus Still Rages

WALL STREET JOURNAL                                                                                               Nov. 21, 2014

By Andrew Morse

ZURICH—Nearly 5,500 people have died from Ebola, the World Health Organization said Friday, adding that the rate of transmission remains intense in the three West African countries at the center of the epidemic.

Medical staff members of the Croix Rouge NGO put on protective suits before collecting the corpse of a victim of Ebola, in Monrovia, Liberia. Agence France-Presse/Getty Images

In an update, the United Nations health agency said 15,351 confirmed, suspected or probable cases of Ebola had been reported in eight countries that have been affected by the disease. Most of the cases were concentrated in Guinea, Liberia and Sierra Leone.

A total of 5,459 people have died of Ebola since the outbreak began, the WHO said. On Wednesday, the WHO reported 15,145 cases and 5,420 deaths.

Ebola’s true overall toll is difficult to gauge because some hard-hit villages are remote and urban centers have showed resistance toward clinics....

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WHO Declares End to Ebola Outbreak in DRC

VOICE OF AMERICA                                                                                                       Nov. 21, 2014

The World Health Organization has declared an end to the Ebola outbreak in the Democratic Republic of Congo.

The outbreak -- unrelated to the one affecting West Africa -- was centered in Congo's northwestern Equateur province and killed at least 49 people.  Nurses from Uganda’s Ministry of Health check passengers arriving from Democratic Republic of Congo, Central Africa at Entebbe Airport Kampala Uganda, Friday, Aug. 8, 2014.

The WHO released a statement Friday saying it has been 42 days, or twice the maximum incubation period, since a new case of Ebola has been detected in the DRC.

The WHO declaration confirms a statement by the DRC government last week that the outbreak there is over.

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http://www.voanews.com/content/who-declares-end-to-ebola-outbreak-in-drc/2529068.html

See complete WHO statement

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