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Small drugmakers can't scale up quickly enough to get ahead of the virus

Two overviews of efforts by drug makers to produce Ebola medication.

WASHINGTON POST                 Oct. 10, 014

by Lenny Bernstein and Brady Dennis

WASHINGTON ..."It takes time. You end up with a situation where the companies weren't set up to ramp up productio. You don't just go from that to making 10,000 does overnight."  -- Prof. Thomas Galsbert, University of Texas Medical Branch at Galveston.

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http://www.washingtonpost.com/national/health-science/small-drugmakers-try-to-scale-up-to-meet-ebola-crisis/2014/10/09/a594dec2-4fee-11e4-babe-e91da079cb8a_story.html

SCIENCE INSIDER                                        Oct. 8, 2014

By Jon Cohen and  Kai Kupferschmidt

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Ebola Outbreak's Grim Equation

THE WASHINGTON POST
by Joel Achenbach, Lena H. Sun and Brady Dennis         October 9

WASHINGTON---  When the experts describe the Ebola disaster, they do so with numbers. The statistics include not just the obvious ones, such as caseloads, deaths and the rate of infection, but also the ones that describe the speed of the global response.

Right now, the math still favors the virus.

 

Global health officials are looking closely at the “reproduction number,” which estimates how many people, on average, will catch the virus from each person stricken with Ebola. The epidemic will begin to decline when that number falls below one. A recent analysis estimated the number at 1.5 to 2.

The number of Ebola cases in West Africa has been doubling about every three weeks. There is little evidence so far that the epidemic is losing momentum.

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US military planes deliver more Marines into Ebola hot zone; African leaders plead for help

ROUNDUP OF DEVELOPMENTS IN THE EBOLA CRISIS

By the  Associated Press                       Oct 10, 2014

An overview of developments in Africa and the West on efforts to counter the epidemic.

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http://www.usnews.com/news/world/articles/2014/10/09/us-military-aircraft-arriving-in-liberia

U.S marines disembark upon their arrival at the Roberts International airport in Monrovia, Liberia, Thursday, Oct. 9, 2014. Six U.S. military planes arrived Thursday at the epicenter of the Ebola crisis, carrying more aid and American Marines into Liberia, the country hardest hit by the deadly disease that has devastated West Africa and stirred anxiety across a fearful world. At a World Bank meeting in Washington, the presidents of several West African countries struggling with Ebola pleaded for help, with one calling the epidemic "a tragedy unforeseen in modern times." (AP Photo/Abbas Dulleh)

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CDC Develops Ebola Modeling Tool While WHO Trains Health Workers

HOMELAND SECURITY TODAY               Oct. 9, 2014

 By Kylie Bull, Managing Editor

The Centers for Disease Control and Prevention (CDC) has developed a dynamic modeling tool called Ebola Response that allows for estimations of projected cases over time in Liberia and Sierra Leone.

 The Ebola Response modeling tool can construct scenarios to illustrate how control and prevention interventions can slow and eventually stop the Ebola epidemic. Importantly, it can help public health and other planners make more informed decisions about emergency response resources to help bring the outbreak under control. The new tool allows input of data reflective of the current situation on the ground in affected countries and communities.

 The Ebola Response modeling tool is intended to help local governments and international responders generate short-term estimates of the Ebola situations in countries, districts and villages. The tool, in the form of a Microsoft Excel spreadsheet, is to be made freely available online.

Meanwhile, in Liberia, the World Health Organization (WHO) has established a new training program for health workers on Ebola care.

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UK to introduce Ebola screening as death of Briton reported in Macedonia

THE GUARDIAN                         Oct. 9, 2014

By Robert Booth

London --Travellers arriving at Heathrow and Gatwick airports from west Africa are to be screened for symptoms of Ebola, Downing Street announced on Thursday night after a day of confusion over the government’s response to the virus that has claimed more than 3,800 lives.

People travelling from the worst-affected countries – Liberia, Sierra Leone and Guinea – will face a questionnaire about their recent travel history, who they have been in contact with and their onward travel arrangements.

 People travelling from Liberia, Sierra Leone and Guinea will be screened for Ebola symptoms.Photograph: Oli Scarff/Getty  Images

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Ebola Cases Surpass 8,000

 

Over 8,000 people in Liberia, Guinea and Sierra Leone have been infected with Ebola, according to new data from the World Health Organization (WHO).

The numbers show there were 2,799 new cases in the last 21 days. Of the 8,011 people infected, 3,857 people have died. “The situation in Guinea, Liberia, and Sierra Leone continues to deteriorate, with widespread and persistent transmission of [Ebola],” says the WHO in a statement.

The WHO cites problems gathering data in Liberia, and says it should be emphasized that “the reported fall in the number of new cases in Liberia over the past three weeks is unlikely to be genuine. Rather, it reflects a deterioration in the ability of overwhelmed responders to record accurate epidemiological data.”

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CDC director calls for action to stop Ebola from becoming “the world’s next AIDS”

WASHINGTON POST                                                   Oct. 9, 2014

WASHINGTON -- Tom Frieden, the director of the Centers for Disease Control and Prevention, compared the Ebola outbreak in West Africa to the AIDS epidemic at a conference Thursday morning at the World Bank.

"In my 30 years in public health, the only thing that has been like this is AIDS," Frieden said at a conference at the World Bank attended by U.N. Secretary-General Ban Ki Moon, Guinean President Alpha Condé, International Monetary Fund managing director Christine Lagarde and representatives of governments and not-for-profit organizations around the world....

"We have to work now so that this is not the world's next AIDS," Frieden warned....

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http://www.washingtonpost.com/blogs/wonkblog/wp/2014/10/09/cdc-director-compares-ebola-to-aids/

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Mobile Technology Key to Containing Ebola in West Africa

VOICE OF AMERICA 

BY Kim Lewis                                                               October 09, 2014

Description of the use of contract tracing and a mobile data collection and messaging software tool that expedites vital information to people in Africa and other regions of the world, in crisis situations.

 

   Workers inside a call center, where people can phone to state their concerns about the Ebola virus, in the city of Monrovia, Liberia, Saturday, Aug. 9, 2014

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http://www.voanews.com/content/ebola-mobile-technology-contacts-tracing-magpi/2477835.html

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European Leaders Scramble to Upgrade Response to Ebola Crisis

NEW YORK TIMES

But, proud of its long record as the world’s biggest donor of humanitarian aid, Europe has since suffered a blow to its self-image of can-do generosity. Its own efforts to contain the lethal virus have been overshadowed  by President Obama’s announcement last month that he was sending  3,000 troops to West Africa to build hospitals and otherwise help in the fight against Ebola.

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Fear of Ebola could have “catastrophic” economic costs, World Bank predicts

Washington POst                                   Oct. 8, 2014
By Max Ehrenfreund

A report issued Wednesday by the World Bank forecasts that the total economic impact of Ebola could exceed $32 billion by the end of 2015 if the virus spreads from Liberia, Guinea and Sierra Leone to neighboring countries.

That single dollar amount doesn't fully convey the extraordinary human toll of a virus that kills four in five of its victims and could infect as many 1.4 million people by January. Yet the World Bank's estimate is a reminder that sickness and death are only part of what could be a developing regional crisis....

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