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Ebola Free-for-All Could Trigger Bad Science and Wasted Efforts

Everybody and his uncle, it seems, has an idea of something that might work to cure people infected with the deadly virus

 SCIENTIFIC AMERICAN    By Helen Branswell                        Dec. 4, 2014

When it comes to treatments for Ebola, there has been a nearly four-decade-long drought. Nothing in the medical arsenal attacks the virus directly....

 

 

 

Dr. John M. Dye, Jr., U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) Viral Immunology branch chief, works in a laboratory at the USAMRIID headquarters in Frederick, Maryland. Dr. Dye is leading a team that is conducting a study with nonhuman primates involving the experimental drug ZMapp, an experimental treatment for Ebola patients. Credit: CDC

 

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Five million children out of school in West Africa due to Ebola

REUTERS-by  Misha Hussain                                   Dec. 3, 2014

DAKAR, Senegal   - Some five million children are out of school in Guinea, Liberia and Sierra Leone because of the deadly Ebola outbreak, according to a report by the Global Business Coalition for Education.

A man walks by a mural with health instructions on treating the Ebola virus, in Monrovia, November 18, 2014. Credit: Reuters/James Giahyue

Schools and other public buildings have been closed because they are believed to increase the spread of the virus. Many are now used as holding centers for Ebola patients.

The report, co-written with A World at School, said being out of school can have a crippling impact on vulnerable children, especially girls, who are more likely to face high-risk situations as a result, including early marriage and pregnancy.

If schools are not reopened, the most vulnerable children will become trapped in a cycle of poverty with devastating consequences for their health and economic development, the report said.

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Finding the Ebola virus’ vulnerable points

Three copies of the Ebola glycoprotein (blue) with antibodies (yellow) latched on to them. Picture by Stanfordby Shalini Saxena - Nov 30 2014 - http://arstechnica.com

We know what antibodies stop it in its tracks—we now know where they attach.

The latest Ebola outbreak has dwarfed any that have occurred since the discovery of the virus in 1976; previous outbreaks have had lethality rates of up to 90 percent. Yet no vaccines or therapies are currently approved for human use, which limits our ability to treat patients and contain the outbreak. Mixtures of monoclonal antibodies (see sidebar) are a potential treatment option that has been used experimentally.

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In Liberia, Ebola Shifts From Cities To Villages

November 30, 2014 - Rachel Martin - npr.org - Copyright © 2014 NPR

Liberia has been a death zone for those exposed to the Ebola virus. NPR's Rachel Martin speaks with correspondent Kelly McEvers about what she saw on the ground, and what she will find hard to forget.

RACHEL MARTIN, HOST:

The death toll in the largest Ebola outbreak in history continues to rise in West Africa. Just this past week, the World Health Organization reported 600 new cases in the three hardest hit countries - Guinea, Sierra Leone and Liberia. Liberia had been the epicenter of the outbreak. But now the country with the largest number of victims is neighboring Sierra Leone. NPR reporters have been covering the story in both countries. NPR's Kelly McEvers is about to finish nearly two weeks in Liberia. She joins us on the line. Hi, Kelly.

Read the whole interview:

http://www.npr.org/2014/11/30/367544593/in-liberia-ebola-shifts-from-cities-to-villages

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U.N. Mission Warns That Ebola Still Poses ‘Huge’ Global Threat

A mother and child stand atop their mattresses in a classroom now used as Ebola isolation ward on Aug. 15, 2014, in Monrovia, Liberiaby Elizabeth Barber - Dec. 1, 2014 - time.com

The U.N. mission is urging that the longer the disease is allowed to storm West Africa, the more likely it is that the virus will reappear elsewhere in the world.

The head of the U.N. Ebola mission in West Africa has said there is a “huge risk” of the Ebola outbreak expanding beyond the hard-hit region.

https://time.com/3611314/u-n-ebola-global-threat-anthony-banbury-bbc/

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WHO Says Liberia, Guinea Meeting Ebola Targets

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Ebola crisis: Struggling to change behaviour in Sierra Leone

BBC   by Andrew Harding                                    Dec. 2, 2014

FREETOWN, Sierra Leone --

... "By now, everyone knows about Ebola; and nobody with symptoms should, logically, be dying at home or on the street anymore.

Sometimes suspected Ebola cases are not reported to the health authorities

They should all have been taken to hospital.

But to understand why that is not happening, all you have to do is drive to any of the impoverished suburbs of Freetown..."

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http://www.bbc.com/news/world-africa-30279932

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There Is An Urgent Need For An Improved Infrastructure To Share Health Data, Researchers Say

DESIGN & TREND  by Randall Mayes                                                                             Nov. 29, 2014

Over the last decade, we have witnessed the emergence of Superbugs, various strains of bird flu and now Ebola, which do not have geographical borders.

Consequently, there is a pressing need for international cooperation to control these pandemics.

In a new study, researchers have identified obstacles that are currently preventing the world from sharing health data, reports Science Daily.

While performing a literature search for the study, an international group of researchers discovered over 1,400 scientific articles related to sharing public health data. From those articles, they found two broad categories that need to be addressed.

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http://www.designntrend.com/articles/28008/20141129/urgent-need-improved-infrastructure-share-health-data.htm

Link to article  in Science Daily
http://www.sciencedaily.com/releases/2014/11/141125102102.htm

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WHO advises male Ebola survivors to abstain from sex

REUTERS                                                                                                                      NOV. 28, 2014

LONDON --Men who recover from Ebola should abstain from sex for three months to minimize the risk of passing the virus on in their semen, the World Health Organization (WHO) said on Friday.

Ebola, a disease that has infected and killing thousands in a vast epidemic in West Africa, normally spreads via bodily fluids such as blood, saliva and faeces. Although sexual transmission of Ebola virus disease has never been documented, the virus has been detected in the survivors' semen.

"Men who have recovered from Ebola virus disease should be aware that seminal fluid may be infectious for as long as three months after onset of symptoms," the WHO said in a statement....

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http://www.reuters.com/article/2014/11/28/us-health-ebola-sex-idUSKCN0JC0UP20141128

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Despite Aid Push, Ebola Is Raging in Sierra Leone

NEW YORK TIMES   By Jeffrey Gettleman                        Nov.28, 2014

KISSI TOWN, Sierra Leone-- ...While health officials say they are making headway against the Ebola epidemic in neighboring Liberia, the disease is still raging in Sierra Leone, despite the big international push. In November alone, the World Health Organization has reported more than 1,800 new cases in this country, about three times as many as in Liberia, which until recently had been the center of the outbreak....

On Freetown’s outskirts, burly youth are setting up roadblocks. The police are nowhere to be found. The young men barricade the road brandishing digital thermometers. Credit Daniel Berehulak for The New York Times

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